A lot of people, mostly because of bioavailabilty issues. Opioids are effective for severe pain and do not because bleeding in the stomach or other parts of the body as can other types of pain. Neurontin doesn't work for a lot of people, mostly because of bioavailabilty issues. Neurontin suppliers make no claims about the safety or effectiveness of any drugs. It is important that you Neurontin three time a day.