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Prednisone typically does not produce immediate effects and must be used for several weeks or even months at a time to get a chronic process under control. Prednisone is used for treating several types of arthritis systemic lupus, allergic reactions, asthma and severe psoriasis. As corticosteroids reduce the normal response of the immune system plays an important role. Prednisolone prevents the release of substances in the body. Prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body. Prednisone is used in so many conditions, only the most common or established uses are mentioned here. If you have any unusual stress such as a serious illness, fever or infection, or if you have a fungal infection anywhere in your body. Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it may still pose a risk to the infant.