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If a woman taking this drug becomes pregnant. There is actually little firm evidence of a relationship. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of depression. A variety of other skin afflictions. Accutane affects the body's processing of fats and sugars. A person's self esteem. You'll need to talk to teenagers about their feelings and self-esteem. While taking Accutane, there should be at least a tow month rest period during which you are off the drug. If you get acne on your body, try not to wear tight clothes, which don't allow skin to breathe and may cause irritation.