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Evidence suggests an imbalance of serotonin, a chemical messenger in the brain that may become unbalanced and cause depression or anxiety. Evidence suggests an imbalance of serotonin, Escitalopram improves symptoms of depression. The morning or in the evening. Lexapro is used to treat depression and generalized anxiety disorder. If left untreated, can cause major problems in your life. Evidence suggests an imbalance of serotonin, a substance in the brain believed to influence mood. There is a serious question about the safety and efficacy of initiating treatment with Lexapro to begin with.