Premarin is also controversial because the health risks to women of absorbing a substance made from equine waste may not be fully known. Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using conjugated estrogens long term, especially if you smoke or are overweight. Conjugated estrogens are used for prevention of osteoporosis in postmenopausal women, and replacement of estrogen in women with ovarian failure or other conditions that cause a lack of natural estrogen in the body. This medication can cause birth defects in an unborn baby.
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